A few changes should be included in the next volume. It would be helpful to have illustrative cases to demonstrate how one literally uses cognitive tests, laboratory tests, and imaging to diagnose patients rather than offering a compilation of information about the tests. The primary care physician’s difficulty in diagnosis is acknowledged in the introduction, and this book could address this difficulty further in future editions. Algorithms and tables could also be used to synthesize information and guide treatment (e.g., a table in chapter 4 for comparing the dose, side effects, cost, and other practical tips of the acetylcholinesterase inhibitors in order to get beyond facts and provide more useful information on using the drugs). In addition, headings are not easy to follow because of the formatting (e.g., chapter 4), and the use of bullets in many chapters is ineffective because of the margins used and the lack of spacing, which prevents quick review of the bulleted items. Finally, space permitting, it would be relevant to provide information on the pros and cons of evaluation and treatment of age-related cognitive decline and mild cognitive impairment, since early detection and treatment may push back the onset of Alzheimer’s disease.