To the Editor: In his letter, Dr. Grucza underlines the importance of appreciating that the relationship of anxiety symptoms and panic disorder to suicide attempts may differ between community samples and inpatient groups. We agree, but with an important caveat. Such comparisons should take into account other clinical factors thought to convey risk for suicidal behavior. One of the major limitations of the studies reviewed in the article by Johnson et al. (1990) was the fact that axis II comorbidity and the aggression/impulsivity dimension were not considered in the evaluation of suicidal status. Both cluster B personality disorder and aggression/impulsivity have been found to be highly associated with suicidal acts (1). A high rate of cluster B personality disorders or aggressive-impulsive traits among the subjects with comorbid depression and panic could bias the studies. We stressed this limitation in the work of Johnson et al. (2). Thus, the assessment of axis I and II disorders and their comorbidity, as well as aggression/impulsivity traits, should be considered when evaluating suicidal risk.