At the recommendation of Drs. Kessing and Andersen, we have reanalyzed our data stratified by sex. We found that the magnitudes of the associations between number of prior mood episodes and risk of subsequent recurrence were nearly identical for men (odds ratio=1.17, 95% confidence interval [CI]=0.87–1.56, p=0.30) and women (odds ratio=1.13, 95% CI=0.97–1.31, p=0.11), which, of course, were similar to the pooled estimate (odds ratio=1.16, 95% CI=1.02–1.31, p=0.02). Nevertheless, because of the reduction in the number of observations and a consequent reduction in statistical power, neither stratified parameter estimate is statistically significant. In contrast, Drs. Kessing and Andersen found an association between number of prior mood episodes and risk of recurrence for women with major depressive disorder but not for men.