"Psychiatrists don’t know a benzene ring from a hole in the wall" was the response of one colleague to whom I showed this book. Although some of my clinical friends may dispute this statement, it is certainly questionable whether chemical structures really constitute useful information in a pocket handbook of drug treatment. The critical reader will find superfluities, deficits, and inaccuracies in almost any text, and this book is certainly no exception. Thirty-five of the 41 chapters provide an alphabetized listing of drugs, from β-adrenergic receptor antagonists to yohimbine, with a somewhat idiosyncratic classification according, in theory, to pharmacological activity and mechanism of action. This avoids the complications associated with the fact that the same drugs are used in the treatment of different disorders (e.g., depression and anxiety). Although there are some advantages to this classification, it assumes that the mechanisms of action of psychiatric drugs are understood. This is an assumption that the most able psychopharmacologist would be loath to make. In practice, there are so many exceptions that most of the chapters address individual drugs, and several others define a drug class on the basis of chemical structure (e.g., tricyclics, benzodiazepines). Dividing the antipsychotics into separate chapters on "dopamine receptor antagonists" and "clozapine" also appears arbitrary.