The book has chapters that thoroughly cover aspects of Alzheimer's disease interspersed with chapters that address neurological mechanisms of disease. In his introduction, Dr. Heston outlines the concept of providing models of disease process that can then be applied more broadly. The bulk of the chapters focus specifically on Alzheimer's disease, the best-known of the more common brain diseases. These chapters cover the disease from the molecular level to patients and those around them. The current data related to epidemiology, pathophysiology, psychopharmacology, and pathology of Alzheimer's disease are thoroughly covered. The language is crisp, clear, and understandable, and the chapters are extensively referenced.