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Paradoxical effects of amitriptyline on borderline patients
Published Online:1 Apr 2006https://doi.org/10.1176/ajp.143.12.1603
Abstract
A paradoxical increase in suicide threats, paranoid ideation, and demanding and assaultive behavior occurred among 15 borderline inpatients receiving amitriptyline in a double-blind study. This pattern differed significantly from that of 14 nonresponding patients receiving placebo.
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