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The American Journal of Psychiatry, VOL. 143, No. 4

REGULAR ARTICLES | April 01, 1986

Concomitant obsessive-compulsive disorder and schizotypal personality disorder

Am J Psychiatry 1986;143:530-532.

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Abstract

Despite advances in the management of patients with obsessive- compulsive disorder, some remain refractory to treatment. The authors retrospectively examined characteristics of 43 treatment-resistant obsessive-compulsive patients and found that those with concomitant schizotypal personality disorder had an extremely high rate of treatment failure. Of the 29 treated nonschizotypal patients, 26 (90%) improved at least moderately; only one of 14 (7%) schizotypal patients improved. In addition, the number of schizotypal features in each patient was strongly negatively correlated with treatment outcome.

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