An earlier report described symptoms and background features in
depressed probands grouped by polarity: bipolar I, bipolar II, and
nonbipolar. The present study made similar comparisons among relatives with
a lifetime history of major depression. The 73 relatives with bipolar II
disorder had the highest rates of marital disruption, psychopathology in
the previous month, nonserious suicide attempts, and nonaffective syndromes
and were the youngest when first treated.