As the hazards of long-term use of psychotropic drugs become more
apparent, drug holidays and medication discontinuance are increasingly
being implemented. Chronically ill patients are often reluctant to
cooperate with such treatment recommendations. The authors questioned 52
chronically impaired patients taking neuroleptics about their attitudes
toward medication changes and their fantasies about the results of
discontinuing their medication. Although they were seemingly compliant, the
majority of the patients anticipated severe negative consequences.