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Human platelet MAO in drug-free and medicated schizophrenic patients

Published Online:https://doi.org/10.1176/ajp.135.8.952

The authors compared platelet monoamine oxidase activity in drug-free chronic and acute schizophrenic patients, medicated chronic schizophrenic patients, and normal controls. A significant decrement in MAO activity was found only in medicated chronic schizophrenic patients. The possible mechanism for this finding is discussed.

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