The authors have developed standardized assessment and control
techniques designed to provide objective measures of tardive dyskinesia in
patients progressing through an experimental treatment program.
Standardized videotaping is carried out and blind ratings on the Abnormal
Involuntary Movement Scale are made by a team of psychiatrists and
neurologists. Other assessments include several measurements of vocal
function and a quantitative acceleration profile standardized on normal
subjects. Such measures allow quantifiable determination of response to
drug treatment and may provide clues to the etiology and definition of the
dyskinetic syndrome.
Abstract Teaser