Ten patients with a diagnosis of pathological intoxication and two with temporal lobe seizures and implanted depth electrodes were studied. An attempt was made to replicate symptomatic behavior and record the EEGs simultaneously. All patients showed clinical intoxication after intravenous administration of alcohol. No abnormalities were observed in patients with pathological intoxication, while patients with implanted electrodes displayed increased abnormal EEG activity. The authors discuss this discrepancy.