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Psychiatric Aspects of Klinefelter's Syndrome
DAVID W. SWANSON; ALBERT H. STIPES
Am J Psychiatry 1969;126:814-822.
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Associate professor, Department of psychiatry, Stritch School of Medicine, Loyola University of Chicago, 2160 South First Ave., Maywood, Ill. 60153 and attending psychiatrist, Veterans Administration Hospital, Hines, Ill.

Resident, Department of psychiatry, Stritch School of Medicine, Loyola University of Chicago, 2160 South First Ave., Maywood, Ill. 60153

1970, American Psychiatric Association

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Abstract

Klinefelter's syndrome is a chromosomal abnormality resulting in hypogonadism. Intellectual impairment and/or neuropsychiatric disorder are present in many cases. The variety of psychopathology accompanying the syndrome is reviewed from the literature and by case reports. The typical individual has a generalized inability to adapt, low social drive, lack of exploratory behavior, and emotional instability. He may also manifest a variety of neurotic, psychotic, and sociopathic behaviors that appear to be compensatory and individual in character.

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