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Articles   |    
The Involutional Depressive Syndrome
SAUL H. ROSENTHAL
Am J Psychiatry 1968;124:21-35.
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Assistant professor of psychiatry and coordinator of psychiatric residency training at the University of Texas Medical School, San Antonio, Tex., as of July 1, 1968

American Psychiatric Association, 1968

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Abstract

Although involutional melancholia is described with precision in the classical textbooks of psychiatry and has been maintained in the official nomenclature, it is uncommonly seen in current practice; some doubt has been expressed that it has ever existed as a distinct clinical entity. The evidence for its existence is reviewed and several explanations are offered for the apparent decline in the incidence of the involutional syndrome: among them, that the early use of effective therapy now prevents the full flowering of the characteristic symptomatology. A reinvestigation of this classical syndrome seems warranted.

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