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The American Journal of Psychiatry, VOL. 124, No. 11

Articles | May 01, 1968

A Study of the Withdrawal of Chlorpromazine or Trifluoperazine in Chronic Schizophrenia

M. R. MORTON

Am J Psychiatry 1968;124:1585-1588.

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Senior psychiatric registrar, John Conolly Hospital, Bristol Road South, Rednal, Birmingham, England

1967-68, American Psychiatric Association

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Abstract

Because the importance of tranquilizing drugs has been difficult to assess precisely, the author undertook a study on the effect of the withdrawal of chlorpromazine and trifluoperazine on hospitalized male schizophrenics in England. Although there were no major relapses among the placebo group, changes occurred that were sometimes disabling.

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