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The American Journal of Psychiatry, VOL. 122, No. 3

Articles | September 01, 1965

TWO-YEAR FOLLOW-UP STUDY OF PROTEIN-BOUND IODINE ELEVATION IN PATIENTS RECEIVING PERPHENAZINE

E. H. CRANSWICK; T. B. COOPER; G. M. SIMPSON

Am J Psychiatry 1965;122:300-305.

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1966 by The American Psychiatric Association

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Abstract

The previous reported finding of elevated PBI in patients receiving perphenazine has been once more confirmed. A marked difference in the finding between pre- and post-1962 has been found. Trace amounts of iodine in perphenazine have been demonstrated and this finding has been discussed. The persistance of this finding up to several years after the initial ingestion of perphenazine has been noted. A tentative hypothesis to explain this phenomenon is given.

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