A study was carried out using meprobamate (Miltown) with 109 psychiatric patients over a period of one year. It was found to be a rapidly acting, safe and effective drug, of distinct benefit in those emotional disturbances which are characterized by the prominence of tension, anxiety and their related symptomatic expressions. Eighty percent of patients benefited from Miltown in relief of symptoms and overall adjustment. Greatest improvement was observed in the acute anxiety reactions where 89% were relieved. Drowsiness in overdosage was the only side effect noted. Blood changes did not occur. The author feels that Miltown is a very satisfactory medication for symptomatic relief of tension and anxiety syndromes, and facilitates other psychotherapeutic procedures.