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The American Journal of Psychiatry, VOL. 97, No. 3

Article | November 01, 1940

FURTHER EXPERIENCES WITH PICROTOXIN AS A CONVULSANT IN THE TREATMENT OF MENTAL ILLNESSES

ABRAHAM A. LOW; ELIZABETH MACDOUGALL; EDWARD ROSS; MANDEL SACHS; DAVID LEVITIN

Am J Psychiatry 1940;97:686-690.

The Psychiatric Institute (H. Douglas Singer, Director) of the Research and Educational Hospitals, the University of Illinois College of Medicine.

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Abstract

1. A report is given of 102 patients treated with picrotoxin as convulsant. 64 of the patients received a combination of picrotoxin with metrazol.2. The combined treatment reduces nausea and vomiting to a minimum. Multiple convulsions occurred in two instances only. Terror was absent, and the paroxysm was induced in a conveniently short time.3. Complications were approximately the same in type and frequency as when picrotoxin or metrazol alone were used.

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