Etkin and Schatzberg examined specificity in the neural correlates of anxiety and depression. Their task presented research participants with conflict by using stimuli that create competing emotional responses (e.g., happy faces with the word "FEAR" written over them or fearful faces with the word "HAPPY"). They found that reaction time slowing decreased as subjects adapted to the conflict. This occurred in healthy subjects and in subjects with major depression but not in those with generalized anxiety disorder. Moreover, while depressed patients resembled healthy subjects in terms of their behavioral slowing, they resembled anxious patients in terms of their cingulate function. Thus, in terms of their neural responses, both anxious and depressed patients showed less adaptation than healthy subjects to the conflicting stimuli, based on levels of engagement in the ventral cingulate cortex. Moreover, the depressed patients' ability to perform normally on this task, despite the presence of abnormal cingulate function, appeared to result from their ability to compensate for a cingulate-based deficit by engaging other prefrontal cortex areas.