In the chapter titled “Spirituality and Depression,” Dan G. Blazer moves from newer definitions of depression focusing on sociocultural contributions toward the increasing rates of depression, the loss of the experience of meaning in life, and the rising contemporary hopelessness. He explains that “the prevailing view among psychiatrists is that people with depression may express their symptoms in terms of religion (depression is an underlying disease, and religion is merely the idiom or vocabulary in which patients express their symptoms)” (p. 11). He recommends that since “spirituality has been thought to be a key to the amelioration of depressive symptoms in many faith traditions,….[t]he clinician should carefully explore the spiritual context from which depressive symptoms emerge, the meaning of the symptoms to the patient, and the complex interplay of traditional psychiatric therapies with the potentially aggravating or nurturing characteristics of the spirituality of the patient” (pp. 17, 18). As an example, in a chapter titled “Substance Use Disorders and Spirituality,” Marc Galanter and Linda Glickman write about the cultural factors involved in peyote rituals and the use of hallucinogens and raves, ayahuasca, ibogaine, cannabis, and betel nuts and make recommendations on how to recognize formal religious observances that may include ritualistic substance use in a controlled way, instead of identifying them as disorders. Of great interest are instruments to assess religion and spirituality, which are extending the empirical base. Among these are the Spiritual Involvement and Belief Scale, the Hood Mysticism Scale, the Spiritual Well-Being Scale, the Royal Free Interview for Religious and Spiritual Beliefs, the Hoge Intrinsic Religious Motivation Scale, and death anxiety scales.