A 32-year study tracking 1,037 children demonstrates that in those who later developed schizophrenia, some cognitive impairments were apparent at age 7 and remained stable, whereas other cognitive problems emerged between childhood and adolescence. Reichenberg et al. (CME, p. 160) report that scores at age 7 for knowledge acquisition, reasoning, and conceptualization were lower in the children who later developed schizophrenia. Differences in attention, processing speed, visual-spatial problem solving, and working memory only became apparent between ages 7 and 13. Dr. Wendy Kates points out important developmental aspects of this study in an editorial on p. 122.