1. A total of 55 cases of dementia præcox were tested by the intravenous injection of prenarcotic doses of sodium amytal prior to treatment with insulin hypoglycemic therapy.2. An ameliorating response to the injection of sodium amytal was obtained in 30 patients and of these 23 or 77 per cent had a favorable therapeutic response to insulin hypoglycemic treatment.3. No ameliorating response to sodium amytal was obtained in 25 cases and of these 16 or 64 per cent failed to respond to insulin treatment.4. The results of metrazol convulsant therapy in cases that failed to respond to insulin treatments are also compared with the sodium amytal test.5. The response to the sodium amytal test appears to be of prognostic value in insulin hypoglycemic shock therapy.6. Plans for further studies are indicated.Abstract Teaser