1. Dehydration was carried out on a series of typical institutional epileptics.2. Dehydration had no definite effect on the occurrence of fits, or on the patient's disposition.3. The giving of unlimited fluids after a period of dehydration, and the forcing of fluids without previous dehydration, had no definite effect on the number of fits.4. The patients were adversely affected by the diet. Preliminary loss of weight was severe. The patients' resistance was lowered. Nitrogen retention either precipitated or complicated stages of excitement and stupor, and acidosis occurred during the excitements.Abstract Teaser