Mr. A, a 35-year-old man who had suffered from schizophrenia since his early 20s, was referred for assessment of refractory auditory verbal hallucinations. He was taking quetiapine, having previously been given several other antipsychotics, including clozapine (which was discontinued after a generalized tonic-clonic seizure and neutropenia). No pharmacological treatments had resulted in significant attenuation of his auditory hallucinations (the predominant clinical symptom of his illness).
The most salient hallucinated voice was perceived solely when Mr. A simultaneously heard real engine sounds from motor vehicles. The engine sounds and the voice were perceived as "in parallel." The "engine voice" spoke to him in the second person, uttering frightening statements such as, "I’ve got hell for you." The timbre of this voice was mechanistic, like the accompanying engine sounds, and lacked human characteristics, such as gender or accent.
Another hallucinated voice occurred simultaneously with actual speech uttered by television announcers. The semantic content was the same as that of the "engine voice," but the "television voice" sounded human, exactly like the real voice of the television announcer who was speaking at the same time. For example, the "television voice" was often described as sounding like an adult woman with a northern British accent and "serious" emotional prosody.
A third variant of Mr. A’s functional auditory hallucinations occurred when he played his electric guitar. Single hallucinated words accompanied the playing (and perception) of each individual musical note. These words were in a seemingly random order, without apparent semantic features. Like the "engine voice," the "guitar voice" lacked human attributes but instead sounded like an electric guitar. For example, if Mr. A played a musical scale, then he would hear hallucinated words whose pitch matched the simultaneously perceived guitar notes. A physical examination, routine blood investigations, and an audiological assessment revealed no abnormalities.