Psychotic, melancholic, and nonmelancholic forms of depression are described. These read like the descriptions of cough classified as wet or dry and productive or nonproductive before Pasteur’s insights set clinicians on the road of bacteriology to antibiotics. Parker describes the commonly accepted neurohumoral model of mood disorders and recommends a smorgasbord of medications and psychotherapies, with a soupçon of physical therapies. Dr. Parker’s patient vignettes are useful for the reader who can see a family member in them. He also offers short lists of mainly Australian Internet sites and reference books.