Depression was measured every 6 months—before, during, and after pregnancy—by structured clinical interview. Depression in the 6 months before pregnancy was not predictive of postpartum depression, suggesting that those who had postpartum depression, in fact, were not depressed just before pregnancy. In addition, because medical records corroborated the subjects’ reports of depression in the clinical interview, we feel confident that our assessment identified those with postpartum depression. However, we agree that the use of an instrument specifically designed to assess postpartum depression would have been optimal and that including a more explicit assessment than we provided would strengthen future studies. We hope that our study will lay the groundwork for additional research on postpartum depression and eating disorders.