First, let’s get one thing straight. This is not a book for most clinicians, unless one needs a sure cure for insomnia. Granted, there are four clinical chapters tacked on at the end (on valproate, lamotrigine, atypical antipsychotics, and calcium channel blockers), but they represent only 12% of the text and appear to be well-written afterthoughts. This is a book for serious scientific types (some of whom may also be clinicians), who will find it as engrossing as the recent presidential election. These are the readers who derive meaning from observations such as, "Incubation of intact human neuroblastoma SH-SY5Y cells with VPA results in an increase in the subsequent in vitro recombinant GSK-3β-mediated [32P] incorporation into two putative GSK-3 substrates (molecular weight ~85 kDa and 200 kDa), compatible with inhibition of endogenous GSK-3β by VPA" (p. 159).