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The American Journal of Psychiatry, VOL. 154, No. 7

REGULAR ARTICLES | July 01, 1997

Cytoarchitecture of the entorhinal cortex in schizophrenia

Am J Psychiatry 1997;154:1010-1012.

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Abstract

OBJECTIVE: The purpose of this study was to determine whether schizophrenia is associated with abnormalities in neuronal migration in the entorhinal cortex. METHOD: Nissl-stained sections through three cytoarchitectonic subdivisions of the entorhinal cortex were examined in postmortem brain specimens from 10 schizophrenic subjects and 10 matched normal comparison subjects. RESULTS: No qualitative differences in cytoarchitecture were observed between the schizophrenic and comparison subjects. CONCLUSIONS: These findings do not replicate previous reports of cytoarchitectural disturbances in the entorhinal cortex of schizophrenic subjects and thus fail to support the hypothesis of abnormal neuronal migration in schizophrenia.

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Cytoarchitecture of the entorhinal cortex in schizophrenia. American Journal of Psychiatry. 1997 Jul;154(7):1010-1012.

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