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The American Journal of Psychiatry, VOL. 151, No. 5

REGULAR ARTICLES | May 01, 1994

Basal ganglia pathology in schizophrenia and tardive dyskinesia: an MRI quantitative study

Am J Psychiatry 1994;151:752-755.

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Abstract

Magnetic resonance imaging was used to measure the volumes of the caudate, putamen, and globus pallidus of 25 schizophrenic patients (17 men and eight women) and 26 age- and sex-matched comparison subjects (18 men and eight women). Schizophrenic patients had significantly larger right and left globus pallidus and right putamen volumes than comparison subjects. There were no significant differences between schizophrenic patients with and without persistent tardive dyskinesia in the volume of any of the three structures.

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