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The American Journal of Psychiatry, VOL. 149, No. 1

Brief Reports | January 01, 1992

Verapamil versus lithium in acute mania

Am J Psychiatry 1992;149:121-122.

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Abstract

Twenty acutely manic patients were studied in a double-blind randomized trial comparing verapamil with lithium. The Petterson Mania Scale, the Brief Psychiatric Rating Scale (BPRS), and the Clinical Global Impression (CGI) were administered before treatment and weekly during 4 weeks of treatment to evaluate response to verapamil and lithium. Both treatment groups improved significantly, and there were no significant overall differences between treatments.

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