Advanced Search

The American Journal of Psychiatry, VOL. 147, No. 7

REGULAR ARTICLES | July 01, 1990

Sertraline in obsessive-compulsive disorder: a double-blind comparison with placebo [published erratum appears in Am J Psychiatry 1990 Oct;147(10):1393]

Am J Psychiatry 1990;147:923-928.

An erratum to this article has been published | view the erratum

Article

text A A A

PDF of the full text article.

Abstract

Many agents that affect the brain's serotonergic system appear to be at least partially effective in the treatment of patients with obsessive- compulsive disorder. However, in this 10-week double-blind trial in which 10 patients received sertraline and nine received placebo, sertraline was ineffective according to four measures of obsessive- compulsive symptoms. The authors discuss the implications of these preliminary findings for the serotonergic theory of obsessive- compulsive disorder and the need to explore the role of other neurochemical systems in this disorder.

Figures in this Article

Your Session has timed out. Please sign back in to continue.

Username

Password

Sign in via Athens (What is this?)

Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.

Forgot Password?

Not a subscriber?

Subscribe Now/Learn More

Purchase Online access to this article for 24 hours

PsychiatryOnline subscription options offer access to the DSM-IV-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.

Submit a Comments

Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of JBJS editorial staff.

* = Required Field

Comment Author(s)*(if multiple authors, separate names by comma)

Example: John Doe

Affiliation & Institution*

Comment Title*

Comment*

Cancel

Topics

Product Recommendation

CME Activity