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The American Journal of Psychiatry, VOL. 147, No. 6

REGULAR ARTICLES | June 01, 1990

Serum prolactin levels during extended cocaine abstinence

Am J Psychiatry 1990;147:777-779.

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Abstract

Following a report indicating almost a 100% risk for hyperprolactinemia in cocaine users after 1 month of abstinence, the authors determined the serum prolactin concentrations of 23 male inpatients who had abstained from cocaine for 2-43 weeks. None showed high prolactin levels; this places the incidence below 12.3% with 95% confidence. These results imply that persistent hyperprolactinemia requires a medical explanation other than cocaine abstinence itself.

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