In a blind family study of 176 probands with nonpsychotic major
depression, psychotic major depression, schizophrenia, or no history of
DSM-III disorders, only the relatives of depressed probands with mood-
incongruent psychotic features had a risk for personality disorders higher
than that for the relatives of never-ill probands. The authors did not find
a high rate of borderline personality in relatives of depressed probands or
of schizotypal personality disorder in relatives of probands with
schizophrenia or any psychosis. However, depressed probands with normal
dexamethasone test results had a significantly higher familial loading for
the DSM-III cluster of histrionic, antisocial, borderline, and narcissistic
personality disorders.Abstract Teaser