A variety of side effects developed in children treated with
neuroleptics for Tourette's disorder. Of 208 children, 34 manifested
dose-related symptoms of dysphoria, nine experienced a worsening of
symptoms of Tourette's disorder that was attributed to akathisia, five
became hostile and aggressive, three developed "fog states" that
disappeared with discontinuation of neuroleptics or treatment with
primidone, and three experienced symptoms of tardive dyskinesia that
resolved with time. This data base of neuroleptic-treated children with
Tourette's disorder demonstrates a variety of subtle and underrecognized
side effects that may not be as readily discernible in children receiving
neuroleptics for a primary psychiatric disorder.Abstract Teaser