The authors compared 10 nondepressed patients with obsessive-compulsive
disorder with 10 normal control subjects of the same sex and similar age
for cerebral glucose metabolic rates obtained using positron emission
tomography. Obsessive-compulsive patients showed significantly elevated
metabolic rates in the whole cerebral hemispheres, heads of the caudate
nuclei, orbital gyri, and the orbital gyri relative to the ipsilateral
hemisphere (the orbital-hemisphere ratio). These results are similar to
those the authors reported previously for another group of
obsessive-compulsive patients and normal control subjects.Abstract Teaser