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The American Journal of Psychiatry, VOL. 145, No. 10

REGULAR ARTICLES | October 01, 1988

An open trial of buspirone in obsessive-compulsive disorder

Am J Psychiatry 1988;145:1285-1286.

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Abstract

Of 14 patients with obsessive-compulsive disorder who entered an 8-week open trial of buspirone, none improved. The ineffectiveness of buspirone may shed light on the serotonergic hypothesis that has been proposed for this disorder.

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