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The American Journal of Psychiatry, VOL. 145, No. 8

REGULAR ARTICLES | August 01, 1988

Occult thyroid dysfunction in patients with refractory depression

Am J Psychiatry 1988;145:1012-1014.

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Abstract

Assessment of metabolic rate was useful in evaluating refractory depression in six of 15 women. Five of the six had normal levels of T3 and T4; however, each had an elevated thyrotropin-stimulating hormone level or a low metabolic rate. The depressions responded to medication with thyroid hormone.

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