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The American Journal of Psychiatry, VOL. 144, No. 2

REGULAR ARTICLES | February 01, 1987

Blunted aldosterone and ACTH release after human CRH administration in depressed patients

Am J Psychiatry 1987;144:229-231.

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Abstract

The authors measured pituitary adrenocortical responses to human corticotropin-releasing hormone (CRH) in 10 patients with a major depressive episode and 10 matched control subjects. Depressed patients had a significantly lower aldosterone and ACTH release, but cortisol and corticosterone responses were not different between groups.

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