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The American Journal of Psychiatry, VOL. 144, No. 8

REGULAR ARTICLES | August 01, 1987

Treatment of severe obsessive-compulsive disorder with fluvoxamine

Am J Psychiatry 1987;144:1059-1061.

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Abstract

Ten obsessive-compulsive patients received single-blind treatment with fluvoxamine, a selective serotonin reuptake inhibitor, for several weeks following at least 2 weeks of placebo. The group showed significant improvement, as measured by several clinical scales and self-ratings; six patients were judged responders. Fluvoxamine appears effective in treating severe obsessive-compulsive disorder.

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