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The American Journal of Psychiatry, VOL. 143, No. 7

REGULAR ARTICLES | July 01, 1986

Essential fatty acid supplementation in tardive dyskinesia

Am J Psychiatry 1986;143:912-914.

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Abstract

Preclinical and clinical observations suggest that enhancement of prostaglandin activity inhibits catecholamine release and may have antidyskinetic effects. A double-blind therapeutic trial with prostaglandin precursor essential fatty acids was conducted in 16 patients with tardive dyskinesia. No beneficial effects were seen.

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