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The American Journal of Psychiatry, VOL. 143, No. 5

REGULAR ARTICLES | May 01, 1986

Alprazolam-induced manic episode in two patients with panic disorder

Am J Psychiatry 1986;143:652-653.

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Abstract

Two patients treated with alprazolam for panic disorder and agoraphobia developed a manic episode. Two biological markers--shortened REM latency and nonsuppression on the dexamethasone suppression test-- suggested that both patients may have had an underlying affective disorder.

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