Of 131 patients with panic disorder or agoraphobia, 44 (34%) had
definite mitral valve prolapse on the basis of clinical findings of an
apical mid- or late systolic click and a murmur and/or a two- dimensional
echocardiogram showing prolapse of one leaflet in two views or of two
leaflets in a single view. Seven other patients (5%) had a probable
diagnosis of mitral prolapse on the basis of a typical murmur alone or an
intermittent apical mid- or late systolic click and a prolapsing leaflet in
a single echocardiographic view. This finding confirms previous reports of
the association between panic disorder and mitral valve prolapse.Abstract Teaser