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The American Journal of Psychiatry, VOL. 142, No. 7

REGULAR ARTICLES | July 01, 1985

Plasma 10-hydroxynortriptyline and ECG changes in elderly depressed patients

Am J Psychiatry 1985;142:866-868.

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Abstract

Among 18 elderly depressed patients given ECGs before and during nortriptyline treatment, plasma E-10-hydroxynortriptyline and the sum of E-10-hydroxynortriptyline and nortriptyline distinguished the group with conduction/repolarization effects. Plasma nortriptyline, age, drug dose, and baseline cardiovascular status did not.

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