While an increase in aggression has frequently been reported in
association with temporal lobe epilepsy, the validity of this behavioral
observation and the relationship of specific aggressive behavior to
electrophysiologic abnormality in the human limbic system remain unclear.
Case reports of five patients document the clinical importance of
aggressive behavior, especially during the interictal period, in patients
with temporal lobe epilepsy. Aggressiveness was often encountered together
with other deepened emotions and changes in behavior previously described
as an interictal behavior syndrome. Variations among the individual
patients may clarify the neuroanatomical mechanisms leading to aggression
and suggest specific therapeutic interventions.Abstract Teaser