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The American Journal of Psychiatry, VOL. 140, No. 2

Special Articles | February 01, 1983

Tardive dyskinesia and anticholinergic drugs

Am J Psychiatry 1983;140:200-202.

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Abstract

The evidence from the literature does not support the notion that psychotropic drugs with central anticholinergic properties (antiparkinsonian drugs, neuroleptics, antidepressants) constitute a risk factor in tardive dyskinesia. Antiparkinsonian drugs tend to produce reversible increases in the severity of dyskinetic movements and can be used as pharmacological probes in the assessment of neuroleptic-induced movement disorders.

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