Investigators have hypothesized that schizophrenic patients have
abnormal left hemisphere function or deviations from normal function
asymmetry. It has also been suggested that schizophrenic patients have
reversal of normal structural asymmetries. The authors measured frontal and
occipital petalia and frontal and occipital width of each hemisphere on the
CT scans of 43 right-handed schizophrenic patients and 40 right-handed
control subjects. There were no significant differences in structural
asymmetry between the groups. The 8 left- handed schizophrenic patients may
have had abnormal functional asymmetries; their mean ventricular-brain
ratio, a possible indirect indicator of cerebral atrophy, was higher than
that of the right-handed patients.Abstract Teaser