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The American Journal of Psychiatry, VOL. 138, No. 1

REGULAR ARTICLES | January 01, 1981

The symptoms of major depressive illness

Am J Psychiatry 1981;138:1-13.

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Abstract

The authors suggest that the common characteristics of various descriptions of major depressive illness--endogenous, endogenomorphic, psychotic, and melancholic--are an autonomous course, a need for biological treatment, and a presumed alteration in neurochemistry. The literature is reviewed to determine those symptoms which best characterize this syndrome. These symptoms may prove useful in developing valid diagnostic criteria for major depressive illness.

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