The authors evaluated the premorbid adjustment of 51 chronic
schizophrenic patients by retrospective chart analysis using a novel scale.
Those patients with CT evidence suggestive of brain atrophy had
significantly worse premorbid scores, particularly during childhood, than
did the patients with normal scans. This finding provides further support
for the clinical relevance of CT findings in chronic schizophrenic patients
and implicates a neuropathological process that occurs early in
development.Abstract Teaser