The authors describe a series of patients with organic brain syndrome
who showed a dramatic clinical response to lithium carbonate therapy. None
of the patients had been diagnosed as manic-depressive. Most had extensive
psychiatric treatment experiences and had been given both affective and
cognitive diagnoses. Six of the eight patients also qualified for the
diagnosis of alcoholism. They had been treated with a wide variety of
psychotherapeutic medications. Lithium was found to be rapidly and
dramatically effective in patients with static lesions of the central
nervous system who showed a combination of dementia and agitated
depression.Abstract Teaser