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The American Journal of Psychiatry, VOL. 136, No. 10

REGULAR ARTICLES | October 01, 1979

Choline chloride treatment of memory deficits in the elderly

Am J Psychiatry 1979;136:1275-1277.

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Abstract

Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performance during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.

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